The effect of repetitive transcranial magnetic stimulation of the cerebellum on the upper limb performance and depressive symptoms in early Parkinson´s disease patients, pilot study
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| Year of publication | 2009 |
| Type | Conference abstract |
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| Description | Object: The aim of this study was to answer if repetitive transcranial magnetic stimulation (rTMS) of cerebellum has had a potential to affect motion of upper limb and symptoms of depression in Parkinsons disease patients. Materials and methods: There were 10 patients in early stage of Parkinson disease (PD) in this study. Every patient underwent one session of rTMS with real stimulation and one session with sham stimulation. We used 1 Hz frequency, total 600 pulses, target of stimulation was lateral right cerebellum. Before and after rTMS patients performed 2 motor tests with their fingers and hands (9 hole peg test, Test with balls) and they filled in Self Rating Depression Scale (Zung). Results: Test with balls had significant difference (p<0.05) in performance with right upper limb and real rTMS (patients need less time after rTMS for this test). There was significant difference (p<0.05) in this test with left upper limb and sham rTMS too (also to need less time to finish this test after rTMS). There were no significant difference in 9 hole peg test, Zung in comparison between after and before (real or sham) rTMS and between real and sham rTMS (with right or left limb). There was no adverse event. Outcome: This pilot study indicate possible influence of rTMS of cerebellum to motor system of upper limb in Parkinsons disease patients. Inhomogenous results can not lead to explicit outcome, but certify for safety and performance of this method. |
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