Thiamine levels and transketolase genetic variants as modifiers of progression of diabetic nephropathy

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Authors	PÁCAL Lukáš TOMANDL Josef TANHÄUSEROVÁ Veronika TOMANDLOVÁ Marie KRUSOVÁ Darja SVOJANOVSKÝ Jan ŠTĚPÁNKOVÁ Soňa BĚLOBRÁDKOVÁ Jana OLŠOVSKÝ Jindřich KAŇKOVÁ Kateřina
Year of publication	2009
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	The specific aims of the study were (i) quantification of plasma and erythrocyte levels of thiamines (Th, ThMP, ThDP), (ii) haplotype-based association study of DN with TKT variability, (iii) genotype vs. phenotype correlation of TKT variability and enzyme erythrocyte activity and (iv) evaluation of prognostic value of those biochemical and genetic parameters for the progression of DN.
Related projects:	Genetic variability of pentose phosphate pathway as a modulating factor of the onset and progression of diabetic nephropathy