Thiamine levels and transketolase genetic variants as modifiers of progression of diabetic nephropathy

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Authors

PÁCAL Lukáš TOMANDL Josef TANHÄUSEROVÁ Veronika TOMANDLOVÁ Marie KRUSOVÁ Darja SVOJANOVSKÝ Jan ŠTĚPÁNKOVÁ Soňa BĚLOBRÁDKOVÁ Jana OLŠOVSKÝ Jindřich KAŇKOVÁ Kateřina

Year of publication 2009
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The specific aims of the study were (i) quantification of plasma and erythrocyte levels of thiamines (Th, ThMP, ThDP), (ii) haplotype-based association study of DN with TKT variability, (iii) genotype vs. phenotype correlation of TKT variability and enzyme erythrocyte activity and (iv) evaluation of prognostic value of those biochemical and genetic parameters for the progression of DN.
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