Characterization of a GM7 glioblastoma cell line showing CD133 positivity and both cytoplasmic and nuclear location of nestin

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Authors

LOJA Tomáš CHLAPEK Petr KUGLÍK Petr PEŠÁKOVÁ Martina OLTOVÁ Alexandra CEJPEK Pavel VESELSKÁ Renata

Year of publication 2009
Type Article in Periodical
Magazine / Source Oncology Reports
MU Faculty or unit

Faculty of Science

Citation
Field Oncology and hematology
Keywords nestin; CD133; intermediate filaments; glioblastoma multiforme; cancer stem cells; immunocytochemistry; transmission electron microscopy
Description A detailed characterization of the established GM7 glioblastoma cell line is given in this paper. This cell line was identified as near-triploid and is characterized by nestin+/CD133+ phenotype with unusual localization of nestin both in cytoplasm and cell nucleus.
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