Two common polymorphisms within the adiponectin gene are associated with food preferences in extremely obese Czech individuals

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Title in English	TWO COMMON POLYMORPHISMS WITHIN THE ADIPONECTIN GENE ARE ASSOCIATED WITH FOOD PREFERENCES IN EXTREMELY OBESE CZECH INDIVIDUALS
Authors	BIENERTOVÁ VAŠKŮ Julie FOREJT Martin TOMANDL Josef BIENERT Petr VAŠKŮ Anna
Year of publication	2008
Type	Article in Proceedings
Conference	1st Central European Congress on Obesity
MU Faculty or unit	Faculty of Medicine
Citation
Field	Genetics and molecular biology
Keywords	adiponectin; polymorphism; extreme obesity; food preferences
Description	Objective: Considering the pivotal role of adiponectin in white adipose tissue metabolism and signaling, we assessed whether the 45T/G and 94T/G polymorphisms within the adiponectin gene influence the food preferences along with basic anthropometric characteristics in the Czech extremely obese population. Conclusions: Both examined polymorphism were significantly associated with various parametres of food intake, above all the total and relative intake of carbohydrates, which could provide possible explanation for the documented prodiabetogenic effects of these polymorphisms. The obtained results well fit into a framework for food intake regulation in relation to adiponectin role and could provide possible targets for further nutrigenomical research and intervention focused on the food preferences.