Behavioural sensitization to methamphetamine affects expression of dopamine D1 receptors in mouse midbrain

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Medicine. Official publication website can be found on muni.cz.

Authors	LANDA Leoš JURAJDA Michal
Year of publication	2008
Type	Article in Periodical
Magazine / Source	The International Journal of Neuropsychopharmacology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	behavioural sensitization; methamphetamine; dopamine D1 receptors; mice
Description	The behavioural part of experiment showed stimulatory influence of methamphetamine (Met) after the acute administration and development of sensitization to Met after repeated treatment. Real-time PCR results showed increased D1 mRNA expression after Met first dose followed by further increase after the last dose of repeated treatment.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.