Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer

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Authors

SVOBODA Miroslav IZAKOVIČOVÁ HOLLÁ Lydie ŠEFR Roman VRTKOVÁ Irena KOCÁKOVÁ Ilona TICHÝ Boris DVOŘÁK Josef

Year of publication 2008
Type Article in Periodical
Magazine / Source International Journal of Oncology
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords micro-RNA; miR125b; miR137; preoperative chemoradiotherapy; rectal cancer
Description The aim of this study was to test the possible involvement of micro-RNAs in response to standard anticancer treatment. Our results for the first time show that higher induced levels of miR125b and miR137 are associated with worse response to the therapy.
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