Capillary Microreaction Method Development for Drug Discovery Support

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Authors

ZEISBERGEROVÁ Marta KONEČNÝ Jiří GLATZ Zdeněk HOOGMARTENS Jos VAN SCHEPDAEL Ann

Year of publication 2008
Type Article in Proceedings
Conference Book of Abstracts 22nd International Symposium on MicroScale Bioseparations and Methods for Systems Biology
MU Faculty or unit

Faculty of Science

Citation
Field Biochemistry
Keywords drug metabolism; microsomes; cytochrome P450; EMMA; microreaction
Description The presented EMMA method could be integrated in preliminary studies at first stage of drug discovery. This method could help to screen new drug candidates. There is no need for radiolabeling, minimal sample preparation and consumption and thus it can speed up data throughput and decrease the operational costs.
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