On-capillary microreaction electrophoretic technique utilizing microsomes as an enzymatic system in drug metabolism studies

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Authors

ZEISBERGEROVÁ Marta KONEČNÝ Jiří GLATZ Zdeněk HOOGMARTENS Jos VAN SCHEPDAEL Ann

Year of publication 2008
Type Article in Proceedings
Conference XII. Setkání biochemiků a molekulárních biologů
MU Faculty or unit

Faculty of Science

Citation
Field Biochemistry
Keywords drug metabolism; microsomes; on-capillary microreaction; electrophoresis
Description Drug metabolism studies performed by the mean of on-capillary microreaction by electrophoretic technique. Enzymatic system of Phase I of biotransformation comprising microsomes as the main source of cytochromes P450 was utilized for examined microreactions.
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