On-capillary microreaction electrophoretic technique utilizing microsomes as an enzymatic system in drug metabolism studies

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Authors	ZEISBERGEROVÁ Marta KONEČNÝ Jiří GLATZ Zdeněk HOOGMARTENS Jos VAN SCHEPDAEL Ann
Year of publication	2008
Type	Article in Proceedings
Conference	XII. Setkání biochemiků a molekulárních biologů
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	drug metabolism; microsomes; on-capillary microreaction; electrophoresis
Description	Drug metabolism studies performed by the mean of on-capillary microreaction by electrophoretic technique. Enzymatic system of Phase I of biotransformation comprising microsomes as the main source of cytochromes P450 was utilized for examined microreactions.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Capillary electrophoresis as a tool for the drug-metabolism studies Integrované bioanalytické technologie pro mikroanalýzy a diagnostiku s využitím LIF a hmotnostní spektrometrie