Automation of biomedical image acquisition and processing in optical microscopy: Exploring the structure and function of human genome
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| Year of publication | 2006 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
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| Description | Biomedical image data can be produced by different instruments. For the exploration of the spatial structure and function of human genome, the most frequent instrument is optical microscope (typically cells or their components stained with fluorescent dyes are observed). The image formed in the microscope is recorded using a special low-light camera, transferred to computer memory and analysed by computer. Although camera is a two-dimensional device, more dimensions can be acquired using scanning (e.g., third spatial dimension, spectral dimension, time dimension or viewing angle dimension). Due to the increasing complexity and volume, the resulting multidimensional data often need computer analysis with a high degree of automation. The talk will attend to the computer analysis of different types of biomedical image data generated by optical microscopy and related automation efforts. It will be accompanied by examples on fixed cells, on live cells as well as on cDNA-microarrays. |
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