Adsorption of oligonucleotides on titanium surface.
| Authors | |
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| Year of publication | 2007 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Titanium is frequently used as a biomaterial for hard tissue replacement, such as dental and orthopaedic implants. The surface morphology influence the final interactions of the implant with the surrounding environment. Recently, we have investigated the application of diffractive optical element (DOE), which is a computer-generated hologram fabricated using advanced electron beam lithography techniques, for sensing a diversity of material properties. Electrochemical impedance spectroscopy (EIS), voltammetry, AFM, and DOE was used for the investigations of adsorption of oligonucleotides on the titanium surface and the effect of mechanical (polished, etched and/or gritted surface) and chemical modification of titanium surface was studied. From the EIS, voltammetric and optical measurements the conclusions of the effect of solvent and physical or chemical modification of titanium surface on the purine (AAG)12 and pyrimidine (TTC)12 oligonucleotide adsorption was delivered. |
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