Testosterone in first-episode schizophrenia

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Authors

ČEŠKOVÁ Eva PŘIKRYL Radovan KAŠPÁREK Tomáš

Year of publication 2007
Type Article in Periodical
Magazine / Source Neuroendocrinology Letters
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords testosterone; first-episode schizophrenia; psychopathology; negative symptoms; treatment
Description During the first psychotic breakdown no significant association was observed either between total testosterone plasma levels and symptoms or treatment reactivity. However, schizophrenia is a heterogeneous disease. In some patients with first-episoede schizophrenia an alteration of psychoendocrinology parameters has been observed. These patients may be more vulnerable to development of enduring negative symptoms, and pharmacotherapy based on neuroendocrinology profile shoud be considered.
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