Arterial blood pressure and baroreflex sensitivity 1-18 years after completing anthracycline therapy
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Neoplasma |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | anthracycline; baroreflex sensitivity; blood pressure; cardiotoxicity |
| Description | The analysis of short-term blood pressure regulation in children, adolescents and young adults 1 to 18 years after the treatment with anthracyclines with cardiotoxic side effects for oncological diseases was the aim of the present study. Thirty-one subjects treated with anthracyclines (PA) and 11 subjects treated with different antitumour drugs (P0) were investigated twice (the interval between two investigations 1 - 9 years). Three hundred and thirty-nine healthy subjects served as controls (C). We concluded (according our results) that the anthracycline antitumour therapy in children decreases blood pressure and within 18 years after the treatment there is not observed a trend toward normal values. BRS was not influenced by the anthracycline therapy. |
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