trans-Bis{2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine-N7}platinum(II) dimethylformamide disolvate

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Authors	TRÁVNÍČEK Z. MAREK Jaromír SZÜČOVÁ L.
Year of publication	2006
Type	Article in Periodical
Magazine / Source	Acta Crystallographica Section E: Structure Reports Online
MU Faculty or unit	Faculty of Science
Citation
Field	Inorganic chemistry
Keywords	cyclin-dependent kinase; CDK inhibitor; anti-cancer; transition metal complex; platinum complex
Description	The title complex, trans-[PtIICl2(C15H16ClN5O)2].2C3H7NO, is centrosymmetric, with square-planar coordination of the Pt atom within a trans-Cl2N2 donor set. The complex is connected through O-H...O hydrogen bonds to two dimethylformamide solvent molecules. The complex is the first structural example of a Pt(II) complex involving two coordinated cyclin-dependent kinase inhibitors, viz. 2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine.
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