A novel quantitative description of electrophysiological processes in guinea pig ventricular cardiomyocytes
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Proceedings |
| Conference | Engineering Mechanics 2005 |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | cardiac cell; tubular system; quantitative modelling |
| Description | A novel quantitative model of a guinea-pig ventricular myocyte has been designed with transverse-axial tubular system (TATS) included. This model displays long-term stability and closely reproduces experimental activity-related changes in action potentials and ionic concentrations inside the cell and in the lumen of the TATS. It allows exploration of species-specific functional consequences of the presence of the TATS in a biophysically realistic way. |
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