Biochemicals changes in aquatic organisms in response to PAHs and their N-heterocyclic derivatives
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Proceedings |
| Conference | Proceeding of 12th International Symposium on Toxicity Assessement |
| MU Faculty or unit | |
| Citation | |
| Field | Environment influence on health |
| Keywords | Daphnia; biomarkers; PAH; N-heterocyclic derivatives |
| Description | N-heterocyclic polycyclic aromatic hydrocarbons are a newly identified class of environmental pollutants with relatively high toxic potential. Here we present our results of acute and chronic toxicity assessment with traditional ecotoxicological model (Daphnia magna) correlated with assessment of biochemical responses. Studied biomarkers in D. magna exposed to parent PAHs and their N-heterocyclic derivatives included glutathione levels and activities of detoxication enzymes (GST, GPx, GR). Our results show suitability of biomarker determination in D. magna as early warning indicators of chronic effects of N-PAHs. Ecotoxicological research of new types of organic pollutants is supported by Grant Agency of the CR (Grant No. 525/03/0367). |
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