Comparison of behavioural effects of amisulpride with selected antidepressants in the mouse model of social interactions

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Authors	PISTOVČÁKOVÁ Jana ŠULCOVÁ Alexandra
Year of publication	2005
Type	Article in Periodical
Magazine / Source	Homeostasis in Health and Diseases
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	amisulpride; antidepressant; behaviour; agonistic interactions; social conflict; mice
Description	The objective of this pre-clinical study was to ascertain behavioural effects of amisulpride in the model of agonistic interactions in mice and compare it with the effects of selected antidepressants in the same animal model. This model is principally based on the conspecific social conflict in male mice. In conclusion, unlike citalopram and valproate, amisulpride at the doses used did not produce antidepressant-like effects in this ethological model in mice, nor did it influence agonistic behaviour in the sense of anxiolytic effects.
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