Interspecies comparison of sensitization to methamphetamine effects on locomotion in mice and rats

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Authors	LANDA Leoš ŠLAIS Karel HANESOVÁ Mariana ŠULCOVÁ Alexandra
Year of publication	2005
Type	Article in Periodical
Magazine / Source	Homeostasis in Health and Diseases
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	begavioural sensitization; interspecies comparison; mice; rats; methamphetamine
Description	The present results indicate development of tolerance ( decreased behavioural response) in rats after repeated administration of methamphetamine in the same dosage regimen used earlier in mice in which a behavioural sensitization (increased behavioural response) was confirmed instead.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.