Big endotelin,interleukin 6 a funkce pravé komory

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Medicine. Official publication website can be found on muni.cz.

Title in English	Big endothelin, interleukin 6 and right ventricle function
Authors	ŠPINAROVÁ Lenka TOMAN Jiří MELUZÍN Jaroslav HUDE Petr KREJČÍ Jan PAVELČÍKOVÁ Hana TOMANDL Josef VÍTOVEC Jiří
Year of publication	2005
Type	Article in Periodical
Magazine / Source	Vnitřní lékařství
MU Faculty or unit	Faculty of Medicine
Citation
Field	Cardiovascular diseases incl. cardiosurgery
Keywords	Big endothelin; interleukin 6; right ventricle
Description	Objective: Big endothelin (BE) and interleukin 6 (IL 6) belong to important active substances, which are related to severity of heart failure. We compared patients with high and low levels of BE and IL 6 in relation to haemodynamics, left (LV) and right ventricle (RV) functions. Population: 155 patients with chronic heart failure, left ventricular ejection fraction (LVEF) below 40 %, NYHA II–IV, mean age 51.8 +- 8.8 years, 129 men, 26 women. 86 patients were diagnosed with ischaemic heart disease (IHD), 69 patients had dilatation cardiomyopathy (DCMP). Conclusion: Big endothelin and interleukin 6 levels are higher in patients who have systolic dysfunction of the left ventricle accompanied with more pronounced disorder of the right ventricle function than in patients who have disorder of the left cardiac ventricle only.
Related projects:	Genetické podklady humorální aktivace u chronického srdečního selhání Early diagnostics and treatment of cardiovascular diseases