Association of variants in angiotensin-converting enzyme and endothelin-1 genes with phototherapy in cutaneous T-cell lymphoma

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Authors

VAŠKŮ Vladimír VAŠKŮ Julie PÁVKOVÁ GOLDBERGOVÁ Monika VAŠKŮ Anna

Year of publication 2004
Type Article in Periodical
Magazine / Source Acta dermatovenerologica
MU Faculty or unit

Faculty of Medicine

Citation
Field Dermatovenerology
Keywords I/D ACE; endothelin-1; gene; polymorphism;mycosis fungoides
Description The cutaneous T-cell lymphoma (CTCL) is a disease characterised by cutaneous infiltrates of malignant, clonally expanded T-cells. Because individual genetic determination of angiogenetic and antioxidant properties of blood vessels could be partly responsible for phototherapy in CTCL patients, three polymorphisms in angiotensin converting enzyme and endothelin-1 genes were determined.
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