A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes

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Authors

LANGHAM Elise CLAYTON Rychard PÁSEK Michal ORCHARD Clive

Year of publication 2004
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The model of rat ventricular myocyte was used to investigate the physiological consequences of acidosis. The results of simulations were in agreement with experimental observations and showed that acidosis causes increase of intracellular Na+, intracellular Ca2+ and amplitude of Cai transients.
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