CD14 promoter polymorphism and atopic phenotypes in Czech young patients with IgE-mediated allergy

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Authors

BUČKOVÁ Dana IZAKOVIČOVÁ HOLLÁ Lydie SCHÜLLER Marcel ZNOJIL Vladimír

Year of publication 2004
Type Article in Proceedings
Conference Abstract Book
MU Faculty or unit

Faculty of Medicine

Citation
Field Immunology
Keywords CD14; gene; polymorphism; IgE; allergy
Description Atopy is a generally considered to be caused by interaction of genetic and environmental factors. The gene encoding CD14 is a positional candidate gene for atopy, as it is localized on chromosome 5q31.1, a region that has been linked to asthma and atopic responses. The present study was conducted to determine the association of -1145A/G polymorphism with atopic phenotypes in the Czech population.
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