Gemcitabine plus cisplain vs. gecitabine plus carboplatin in stage IIIb and IV non small cell lung cancer: A phase III randomized trial

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Authors	ZATLOUKAL Petr PETRUŽELKA Luboš ZEMANOVÁ Milada KOLEK Vítězslav SKŘIČKOVÁ Jana PEŠEK Miloš FOITŮ Hana GRYGÁRKOVÁ Ivona SIXTOVÁ Dimka ROUBEC Jaromír
Year of publication	2003
Type	Article in Periodical
Magazine / Source	Lung Cancer
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pneumology
Keywords	non small cell lung cancer; gemcitabine; carboplatin; cisplatin; phase III trial
Description	The randomized multicenter trial was conducted to compare the tolerability of gemcitabine plus cisplatin GP vs. gemcitabine plus carboplatin GC in chemonaive stage IIIb and IV pts. The enrolled pts, 87 in the GP branch and 89 in GC branch, were balanced demographically and for disease characteristics. Results show that that both regimens were comparable. GC may offer acceptable option for patients unable to receive cisplatin.
Related projects:	Environment - carcinogenesis - oncology