Autonomous regulation of circulation in children and adolescents after antitumour therapy

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Authors

ZÁVODNÁ Eva HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana HRSTKOVÁ Hana

Year of publication 2003
Type Article in Proceedings
Conference 3rdFEPS Congress, Nice (France) 2003
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords antitumour therapy; baroreflex sensitivity; blood pressure variability; heart rate variability
Description The aim of the study was the comparison of body and circulatory parameters in healthy subjects (C), and subjects who were previously treated for a malignant tumour (T) with respect to plasmatic lipids in T group. The T group had increased parasympathetic and decreased sympathetic tonic activity, and decreased baroreflex senstitivity than C. The increased variability of heart rate could be explain by an increase of parasympathetic tonic control of the heart. The cirulatory changes did not bear on obesity, but they were rather specific effect of antitumour treatment.
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