Využití in situ technik v analýze telomer nádorových buněk
| Title in English | Aplication in situ techniques in analysis of telomeres of tumor cells |
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| Authors | |
| Year of publication | 2003 |
| Type | Article in Proceedings |
| Conference | Analytická cytometrie II |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | telomeres; FISH; fiber-FISH; PRINS |
| Description | For indefinite cellular proliferation of germline and tumour cells is essential stable telomere maintenance.In most cases, telomere synthesis is performed by telomerase, that results in stabilisation of telomeres.Analysis of telomeres by in situ techniques enables to distinguish between these two mechanisms and analyzes individual telomeres of appropriate cells. |
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