The role of transverse-axial tubular system in ventricular cardiac cell arrhythmogenesis: A simulation study

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Authors

PÁSEK Michal CHRISTÉ Georges ŠIMURDA Jiří

Year of publication 2002
Type Article in Proceedings
Conference Biomechanics of man 2002
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords cardiac cell; transverse-axial tubular system; quantitative modelling
Description A mathematical model of electrical activity of ventricular cardiac cell including a quantitative description of the transverse-axial tubular system (TAT-system) function is presented. The results of model simulations indicated that the TAT-system can play a role in arrhythmogenesis. Under different conditions the effect can be adverse or protective against initiations of ectopic arrhythmias.
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