The role of transverse-axial tubular system in ventricular cardiac cell arrhythmogenesis: A simulation study

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Authors	PÁSEK Michal CHRISTÉ Georges ŠIMURDA Jiří
Year of publication	2002
Type	Article in Proceedings
Conference	Biomechanics of man 2002
MU Faculty or unit	Faculty of Medicine
Citation
Field	Physiology
Keywords	cardiac cell; transverse-axial tubular system; quantitative modelling
Description	A mathematical model of electrical activity of ventricular cardiac cell including a quantitative description of the transverse-axial tubular system (TAT-system) function is presented. The results of model simulations indicated that the TAT-system can play a role in arrhythmogenesis. Under different conditions the effect can be adverse or protective against initiations of ectopic arrhythmias.
Related projects:	Quantitative analysis of effect of tubular system on electrical activity of cardiac cells Early diagnostics of Cardiovascular Diseases