The assessment of cardioprotective effect of dexrazoxane (ICRF-187) againts late antrhracycline cardiotoxicity in patients treated for childhood cancer

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Medicine. Official publication website can be found on muni.cz.

Title in English	The assessment of cardioprotective effect of dexrazoxane (ICRF-187) against late anthracycline cardiotoxicity in patients treated for childhood cancer.
Authors	ELBL Lubomír HRSTKOVÁ Hana NOVOTNÝ Jan CHALOUPKA Václav
Year of publication	2003
Type	Article in Periodical
Magazine / Source	European Journal of Echocardiography
MU Faculty or unit	Faculty of Medicine
Citation
Description	Clinical cardiotoxicity was found in 4 pts (5%) from group II. After exclusion of these patients wd have not found any difference in rest EF among groups. MPI was worsened in both groups in the compařrison to the controls (p-0,01) and IRT was prolonged in group II (p-0,05)). The increment in EF to dynamic stress was similar in pts and controls (12% group I,16% group II, 18% controls). On the contrary, debulamine stress revealed in 63% of cases the pathological response in patients. An inadequate response of MPI and ESS was present in pts withouuuut cardioprotection.