Autonomous regulation of circulation in children after anthracycline therapy

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Authors

ZÁVODNÁ Eva HRSTKOVÁ Hana HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana

Year of publication 2002
Type Article in Periodical
Magazine / Source Scripta Medica
MU Faculty or unit

Faculty of Medicine

Citation
Field Paediatry
Keywords Baroreflex sensitivity; heart rate variability; blood pressure variability; anthracycline
Description In this study, we evaluated the development of autonomous regulation of circulation in children who had previously been treated for malignantt diseases, particularly leukaemia. The relationship between BRS and PI and between BRS and BP were suppressed, thus demonstrating the association of anthracycline treatment with changes in cardiovascular functions. Body growth was decreased in all children after anti-cancer therapy, and blood pressure was lower only in the children who had anti-cancer anthracycline therapy.
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