Baroreflex sensitivity, blood pressure and heart rate variability in children and adolescents after anthracycline treatment.

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Authors

HRSTKOVÁ Hana HONZÍKOVÁ Nataša FIŠER Bohumil NOVÁKOVÁ Zuzana

Year of publication 2001
Type Article in Periodical
Magazine / Source Scripta medica
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords Leukaemia; anthracycline; baroreflex sensitivity; blood pressure; age
Description Age related changes of systolic (SBP) and diastolic (DBP) blood pressure, mean cardiac interval (PI) and baroreflex sensitivity in ms/mmHg (BRS) and in Hz/mmHg (BRSf) after anthracycline treatment were monitored. The values of 20 children treated with anthracyclines were compared with those treated with a non-anthracycline medication (16 patients) and 177 health controls.The age-dependent increase of SBP, DBP, PI and the decrease of BRSf were observed in all groups. The age-dependent increase of SBP was decelerated in children treated with anthracycline.
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