Vztah TaqI A polymorfizmu genu pro DRD2 k alkoholizmu: podvod 20. století?

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Title in English The relationship between the TaqI A polymorphism of the DRD2 gene and alcoholism: deceit of the XX. century?
Authors

ŠERÝ Omar NOVOTNÝ Miroslav KAŠPAROVSKÁ Jitka POPOV Petr TOUFAROVÁ Jana HORNOVÁ Lucie ZVOLSKÝ Petr

Year of publication 2001
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords alcoholism DRD2 polymorphism
Description We tried to assess the association between the TaqI A polymorphism of DRD2 gene and the alcohol dependence in the group of 295 subjects (164 controls and 131 alcoholics), unrelated Caucasians from the Czech Republic. Any association between TaqI A polymorphism and alcohol dependence was detected. However, we find some errors in the methodology of some studies that publicised about significant association of the TaqI A polymorphism to the alcohol dependence. These errors are discussed in the introduction. We propose a new reappraisal of these studies.
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