Adsorptive Stripping Analysis of DNA with Admittance Detection

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Authors	JELEN František VETTERL Vladimír BĚLUŠA Petr HASOŇ Stanislav
Year of publication	2000
Type	Article in Periodical
Magazine / Source	Electroanalysis
MU Faculty or unit	Faculty of Science
Citation
Field	Biophysics
Keywords	voltammetric analysis; DNA; admittance measurements; DNA damage
Description	Native, denatured and damaged calf thymus DNA was studied by admittance measurement using hanging mercury drop electrode. The obtained results suggest that in damaged regions of double stranded native DNA the bases are accesible for the interaction with the electrode producing peak 3 without passing through the potential region U around -1.2 V, where double stranded DNA is supposed to be slowly opened.
Related projects:	Structure and Interaction of Nucleic Acids on Metal Surfaces Adsorption of bases, nucleosides, nucleotides and polynucleotides on electrods