Frekvence protilátek proti glykoproteinům trombocytární membrány vyšetřených metodou MAIPA u dětí s imunní trombocytopenickou purpurou.

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Title in English	The Frequency of Antiglycoprotein antibodies established by the MAIPA Method in children with immune trombocytopenia
Authors	POSPÍŠILOVÁ Dagmar MIHÁL Vladimír PETRTÝLOVÁ Kamila STARÝ Jan PTOSZKOVÁ Hana HAK Josef TOUŠOVSKÁ K. HRSTKOVÁ Hana PROCHÁZKOVÁ Daniela SULOVSKÁ I. AMBRŮZOVÁ Z.
Year of publication	2000
Type	Article in Periodical
Magazine / Source	Česko - Slovenská Pediatrie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Paediatry
Keywords	immune thrombocytopenia; antiplatelet antibodies; MAIPA; platelet glycoproteins
Description	Persisting positivity of antibodies in acute ITP was in correlation with the didease chronicity. Antibody positivity in patients inremission could be in sign of relapse risk and therofore needs creful follow-up. The sensitivity of direct MAIPA on our cohort of chronic ITP children 53% and only 31% in acute ITP and the specifility for chronic ITP is 82%. The sensitivity of indirect MAIPA is low, only 23% in chronic ITP and 17% in acute ITP.Platelet-associated and serum antibodies should be tested simultancously to get more precide results for interpretation.