A web-based bioinformatic tool LYNX for targeted LYmphoid NeXt- generation sequencing data analysis and visualization for hematooncology.

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Authors	REIGL Tomáš PORC Jakub Paweł NAVRKALOVÁ Veronika HYNŠT Jakub PÁL Karol STRÁNSKÁ Kamila KOTAŠKOVÁ Jana POSPÍŠILOVÁ Šárka PLEVOVÁ Karla
Year of publication	2023
Type	Conference abstract
MU Faculty or unit	Central European Institute of Technology
Citation
Description	Next-generation sequencing (NGS) is one of the most rapidly expanding technologies in laboratory medicine. In routine diagnostics, a single NGS experiment can replace several laboratory tests and provide more information about the disease being tested. Commonly, the assistance of a qualified bioinformatician or a dedicated tool is necessary for the data analysis. Our team has created an integrative, targeted NGS panel that detects genetic markers common for most abundant lymphoid malignancies (PMID: 34082072). For this panel, we have developed a bioinformatic tool, LYNX, with a user interface (UI) that allows diagnosticians to easily analyze the data and interactively visualize the results. This facilitates data interpretation and speeds up diagnostic procedures.
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