Effects of various serotonin agonists, antagonists, and uptake inhibitors on the discriminative stimulus effects of methamphetamine in rats

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Authors

MUNZAR Patrik LAUFERT Michael D. KUTKAT Scott W. NOVÁKOVÁ Jana GOLDBERG Steven R.

Year of publication 1999
Type Article in Periodical
Magazine / Source The Journal of Pharmacology and Exper. Therapeutics
MU Faculty or unit

Faculty of Medicine

Citation
Web https://jpet.aspetjournals.org/content/291/1/239.long
Field Pharmacology and pharmaceutical chemistry
Keywords Rats; methamphetamine; serotonin agonists; serotonin antagonists; serotonin uptake inhibitors; discriminative behaviour
Description The present data suggest that the 5-HT system plays a modulatory role in the discriminative stimulus effects of methamphetamine. These effects appear to be mediated through 5-HT release and blockade of reuptake and subsequent activation of 5-HT(2A/2C) receptors, with limited involvement of other 5-HT receptor subtypes.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info