Olfactory Bulbectomy Model of Depression Lowers Responding for Food in Male and Female Rats: The Modulating Role of Caloric Restriction and Response Requirement

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Authors	FATTORE Liana AMCHOVÁ Petra FADDA Paola RUDÁ Jana
Year of publication	2023
Type	Article in Periodical
Magazine / Source	BIOMEDICINES
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://www.mdpi.com/2227-9059/11/9/2481
Doi	http://dx.doi.org/10.3390/biomedicines11092481
Keywords	olfactory bulbectomy; depression; reward; self-administration; sex; strain
Description	In summary, this study showed that bulbectomy significantly reduces operant responding and food intake in male and female Sprague–Dawley rats while inducing a mild reducing effect only in the Wistar strain.
Related projects:	Preclinical and clinical research in pharmacokinetics, neuropsychopharmacology and personalized pharmacotherapy in oncology