Quality control of clinical-grade human embryonic stem cells

Investor logo

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Authors

SOURALOVÁ Tereza VENTRUBA Pavel JEŠETA Michal ŘEHÁKOVÁ Daniela HAMPL Aleš KOUTNÁ Irena

Year of publication 2023
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Medicine

Citation
Description Human embryonic stem cells are able to differentiate into every cell type in the human body making them a tremendous cell source for regenerative medicine. However, the production of human embryonic stem cell lines for clinical use is challenging as clean rooms, highly-qualified personnel, and standard operating procedures for both manufacture and quality control are required. Here we present the quality control of clinical-grade hESC lines that were derived in xeno-free, feeder-free conditions, and according to current good manufacturing practices. In-depth quality control provides essential information about the safety, pluripotency, and differentiation potential of lines and it is a necessary component of new clinical-grade hESC line establishment.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info