Mass Spectrometry Imaging Techniques Enabling Visualization of Lipid Isomers in Biological Tissues

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Authors	BEDNAŘÍK Antonín PRYSIAZHNYI Vadym BEZDEKOVÁ Dominika SOLTWISCH Jens DREISEWERD Klaus PREISLER Jan
Year of publication	2022
Type	Article in Periodical
Magazine / Source	Analytical Chemistry
MU Faculty or unit	Faculty of Science
Citation	BEDNAŘÍK, Antonín, Vadym PRYSIAZHNYI, Dominika BEZDEKOVÁ, Jens SOLTWISCH, Klaus DREISEWERD and Jan PREISLER. Mass Spectrometry Imaging Techniques Enabling Visualization of Lipid Isomers in Biological Tissues. Analytical Chemistry. American Chemical Society, 2022, vol. 94, No 12, p. 4889-4900. ISSN 0003-2700. Available from: https://dx.doi.org/10.1021/acs.analchem.1c05108.
web	https://pubs.acs.org/doi/10.1021/acs.analchem.1c05108
Doi	http://dx.doi.org/10.1021/acs.analchem.1c05108
Keywords	mass spectrometry imaging; lipid isomers; double bond position; sn-position; chemical derivatization; biological tissues
Description	The feature article focuses on a review of recent developments in mass spectrometry imaging (MSI) of lipid isomers in biological tissues. The tandem MS techniques utilizing on-line and off-line chemical derivatization procedures, ion activation techniques such as ozone-induced dissociation (OzID), ultraviolet photodissociation (UVPD), or electron-induced dissociation (EID), and other techniques such as coupling of ion mobility with MSI are discussed. The importance of resolving lipid isomers in diseases is highlighted.
Related projects:	MALDI MS zobrazování izomerů lipidů lišících se pozicí dvojné vazby uhlík-uhlík