Short-term complications of percutaneous biliary interventions in patients with cholangiocarcinoma in dependence on presence of gastroenteroanastomosis

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Authors

STRAKA Matej ROHAN Tomáš ANDRAŠINA Tomáš MATKULČÍK Peter SVOBODA Martin PROCHÁZKA Vladimír

Year of publication 2021
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Purpose: To analyze short-term complications rate after percutaneous biliary drainage (PTD) in cholangiocarcinoma (CCC) in relation to history of surgically performed gastroenteroanastomosis (GEA) Materials and Methods: 136 patients with CCC with palliative percutaneous interventions (i.e. PTD, brachytherapy, stent implantations) performed between 2005-2019 were enrolled in this single center retrospective study. Study group consists of patients with GEA performed prior to percutaneous biliary intervention (n=8). Control group consists of 128 patients with CCC without history of any prior hepatobilliary surgical procedure. 30 day complication rate (i.e. biliary leakage, bilioma formation, haemobilia, etc.) after percutaneous intervention was assessed. Complications per patient and complication per procedure in both groups were compared (Chi-Square Test). Results: A total of 386 percutaneous transhepatic interventions were performed, 27 in GEA and 359 in control group (average 3.37 vs 2.82 per patient). Metal stent was implanted in 88% of patients with GEA and in 54% of control group (p=0.33), brachytherapy was performed in 38% and 43% of patients (p=0.87). Overall complication rate per procedure and per patient was 11.3% and 22.0%, respectively. Signifcant diference in complication rate per patient was observed (26% vs 10%; p=0.013), on the contrary, complication rate per procedure was not signifcant (38% vs 21%; p=0.28). Conclusion: Patients with CCC treated by paliative transhepatic procedures with history of GEA showed signifcantly higher rate of periprocedural complications
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