CBD is not converted to THC in rats: A framework interpretation and discussion

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Authors	VACEK Jan PAPOUSKOVA Barbora HOLCOVÁ POLANSKÁ Hana HÖNIGOVÁ Kateřina STORCH Jan BABULA Petr MASAŘÍK Michal
Year of publication	2021
Type	Article in Periodical
Magazine / Source	European Neuropsychopharmacology
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://www.sciencedirect.com/science/article/pii/S0924977X21001917?via%3Dihub
Doi	http://dx.doi.org/10.1016/j.euroneuro.2021.04.003
Keywords	CBD; THC; rats
Description	Cannabidiol (CBD) is a non-psychotropic exogenous cannabinoid that is an active component in a number of topical and oral preparations. The pharmacological potential of CBD is determined by its anti-inflammatory and immuno- or neuromodulatory activities. This natural terpenoid is widely used today, and therefore more attention is now paid to examining its safety after the administration of high doses (Epidiolex) and also after low-dose chronic exposure, e.g. in the form of food supplements. CBD is therefore a molecule that has recently gained a great deal of scientific interest, both at the level of basic research and industrial development.