In Comparison to Pathological Q Waves, Selvester Score Is a Superior Diagnostic Indicator of Increased Long-Term Mortality Risk in ST Elevation Myocardial Infarction Patients Treated with Primary Coronary Intervention

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Authors

HOLICKÁ Mária ČUČKOVÁ Pavla HNATKOVA Katerina KOC Lumír ONDRÚŠ Tomáš LOKAJ Petr PAŘENICA Jiří NOVOTNÝ Tomáš KALA Petr MALÍK Marek

Year of publication 2021
Type Article in Periodical
Magazine / Source Diagnostics
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.mdpi.com/2075-4418/11/5/799
Doi http://dx.doi.org/10.3390/diagnostics11050799
Keywords primary percutaneous coronary intervention; Q wave; Selvester score; ST elevation myocardial infarction
Description The development of pathological Q waves has long been correlated with worsened outcome in patients with ST elevation myocardial infarction (STEMI). In this study, we investigated long-term mortality of STEMI patients treated by primary percutaneous coronary intervention (PPCI) and compared predictive values of Q waves and of Selvester score for infarct volume estimation. Data of 283 consecutive STEMI patients (103 females) treated by PPCI were analysed. The presence of pathological Q wave was evaluated in pre-discharge electrocardiograms (ECGs) recorded >= 72 h after the chest pain onset (72 h Q). The Selvester score was evaluated in acute ECGs (acute Selvester score) and in the pre-discharge ECGs (72 h Selvester score). The results were related to total mortality and to clinical and laboratory variables. A 72 h Q presence and 72 h Selvester score >= 6 was observed in 184 (65.02%) and 143 (50.53%) patients, respectively. During a follow-up of 5.69 +/- 0.66 years, 36 (12.7%) patients died. Multivariably, 72 h Selvester score >= 6 was a strong independent predictor of death, while a predictive value of the 72 h Q wave was absent. In high-risk subpopulations defined by clinical and laboratory variables, the differences in total mortality were highly significant (p < 0.01 for all subgroups) when stratified by 72 h Selvester score >= 6. On the contrary, the additional risk-prediction by 72 h Q presence was either absent or only borderline. In contemporarily treated STEMI patients, Selvester score is a strong independent predictor of long-term all-cause mortality. On the contrary, the prognostic value of Q-wave presence appears limited in contemporarily treated STEMI patients.
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