Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials

Investor logo
Investor logo
Investor logo

Warning

This publication doesn't include Faculty of Sports Studies. It includes Faculty of Science. Official publication website can be found on muni.cz.
Authors

WEINSTAIN Roy SLANINA Tomáš KAND Dnyaneshwar KLÁN Petr

Year of publication 2020
Type Article in Periodical
Magazine / Source Chemical reviews
MU Faculty or unit

Faculty of Science

Citation
Web https://doi.org/10.1021/acs.chemrev.0c00663
Doi http://dx.doi.org/10.1021/acs.chemrev.0c00663
Keywords Reaction products; Absorption; Phosphates; Aromatic compounds; pH
Attached files
Description Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years have seen the development of PPGs activatable by biologically and chemically benign visible and near-infrared (NIR) light. These long-wavelength-absorbing moieties expand the applicability of this powerful method and its accessibility to non-specialist users. This review comprehensively covers organic and transition metal-containing photoactivatable compounds (complexes) that absorb in the visible- and NIR-range to release various leaving groups and gasotransmitters (carbon monoxide, nitric oxide, and hydrogen sulfide). The text also covers visible- and NIR-light-induced photosensitized release using molecular sensitizers, quantum dots, and upconversion and second-harmonic nanoparticles, as well as release via photodynamic (photooxygenation by singlet oxygen) and photothermal effects. Release from photo-activatable polymers, micelles, vesicles, and photoswitches, along with the related emerging field of photopharmacology, is discussed at the end of the review.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info