Comparison of whole exome sequencing and FoundationOne Heme sequencing panel as tools for precision oncology in paediatric patients with difficult-to-treat solid tumours

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Authors	NOSKOVA H. ADAMCOVÁ Soňa KNOFLÍČKOVÁ Dana PÁL Karol GRIONI Andrea HORNAKOVA T. MERTA T. MUDRY P. PAVELKA Z. VEJMELKOVA K. STERBA J. SLABÝ Ondřej
Year of publication	2019
Type	Conference abstract
MU Faculty or unit	Central European Institute of Technology
Citation
Description	The necessary condition for the application of precision oncology approach into the routine is a detailed molecular characterization of the tumour. In our study, we explored clinical applicability of both whole exome sequencing (WES) and FoundationOne Heme (F1Heme) panel (Foundation Medicine, Inc., MA, USA) as comprehensive genomic profiling tools in a cohort of 35 children with difficult-to-treat solid tumours.
Related projects:	Sekvenování nové generace a expresní profilování jako diagnostický podklad pro návrhy individualizovaných léčebných plánů pro děti se solidními nádory