Hydrophilic Poly(2-Oxazoline) Coatings Prepared By Non-Equilibrium “Cold” Atmospheric Pressure Plasma

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Authors	ŠRÁMKOVÁ Petra ZAHORANOVÁ Anna KELAR Jakub KELAR TUČEKOVÁ Zlata STUPAVSKÁ Monika JURMANOVÁ Jana KOVÁČIK Dušan ČERNÁK Mirko
Year of publication	2019
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Due to biological inertness and excellent stability, polytetrafluoroethylene (PTFE) is extensively used for the manufacturing of vascular grafts and various implants. However, its highly hydrophobic nature is disadvantageous for specific biomedical applications requiring the control of the proteins or cell adhesion. Hydrophobicity can be decreased by surface modification using the various biocompatible polymers. In our contribution, we proposed the new method for PTFE surface coating by synthetic hydrophilic polymers, so-called poly(2-oxazolines) (POx). Immobilization of the POx layer was performed employing non-equilibrium “cold” atmospheric pressure plasma generated by the diffuse coplanar surface barrier discharge (DCSBD). Our main objective was to achieve the stable and biologically active cross-linked POx layer immobilized on the PTFE surface. This study provides a new approach for the preparation of POx coatings, which is faster, easier, and more environmentally friendly in comparison to traditional grafting methods or plasma-assisted polymerization.
Related projects:	Postdoc@MUNI