Drug interference in Trinder reaction

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Authors

WIEWIORKA Ondřej DASTYCH Milan ČERMÁKOVÁ Zdeňka

Year of publication 2017
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Attached files
Description Our recent research of drug interference in Trinder reaction – a widely used chromogenic reaction in the field of clinical biochemistry, was focused on comparison of various drugs and the impact on determination of several biochemical parameters with validated diagnostic kits utilizing Trinder reaction. Our results showed significant alteration of results in therapeutic concentrations of ACC®, Dicynone® and Novalgin® in comparison to the control samples. Dobutamine, Tensamin and ascorbic acid showed significant interference only in samples containing 1 mmol/l of drug.
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