Drug interference in Trinder reaction

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Authors	WIEWIORKA Ondřej DASTYCH Milan ČERMÁKOVÁ Zdeňka
Year of publication	2017
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Attached files	268672_Wiewiorka_Trinder_reaction.pdf
Description	Our recent research of drug interference in Trinder reaction – a widely used chromogenic reaction in the field of clinical biochemistry, was focused on comparison of various drugs and the impact on determination of several biochemical parameters with validated diagnostic kits utilizing Trinder reaction. Our results showed significant alteration of results in therapeutic concentrations of ACC®, Dicynone® and Novalgin® in comparison to the control samples. Dobutamine, Tensamin and ascorbic acid showed significant interference only in samples containing 1 mmol/l of drug.
Related projects:	Příspěvek chemických a biochemických metodik ke studiu molekulární podstaty vybraných patologických stavů a onemocnění