Stanovení vývojového potenciálu lidských embryí pomocí omických disciplín

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Title in English	'Omics' techniques: Genomics, Transcriptomics, Proteomics and Metabolomics in Embryo Developmental Capacity Assessment
Authors	MÁDR Aleš GLATZ Zdeněk CRHA Igor
Year of publication	2017
Type	Article in Periodical
Magazine / Source	Chemické listy
MU Faculty or unit	Faculty of Science
Citation
Field	Biochemistry
Keywords	assisted reproduction; human embryo; in vitro fertilization; genomics; transcriptomics; proteomics; metabolomics;
Description	This review defines limits of currently used techniques to assess developmental capacity of human embryos in assisted reproduction and provides an overview of techniques assessing embryo’s physiology on levels of genomics, transcriptomics, proteomics and metabolomics. Basic principles of respective techniques are covered and discovered biomarkers are discussed with respect to biochemical functions and its prognostic value of embryonal development.
Related projects:	Centrum pokročilých bioanalytických technologií Podpora biochemického výzkumu v roce 2017