Asymptomatic Elevation of Amylase and Lipase After Olanzapine Treatment

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Authors

USTOHAL Libor MAYEROVÁ Michaela VALKOVÁ Barbora SEDLÁKOVÁ Hana KAŠPÁREK Tomáš

Year of publication 2016
Type Article in Periodical
Magazine / Source JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
MU Faculty or unit

Central European Institute of Technology

Citation
Web http://journals.lww.com/psychopharmacology/Citation/2016/04000/Asymptomatic_Elevation_of_Amylase_and_Lipase_After.18.aspx
Doi http://dx.doi.org/10.1097/JCP.0000000000000460
Field Pharmacology and pharmaceutical chemistry
Keywords ACUTE-PANCREATITIS
Description Olanzapine, an atypical antipsychotic,has been considered one of the most efficient antipsychotic drugs, and it is the most frequently prescribed. It is categorized as a multiacting receptor targeted antipsychotic. The most significant adverse effects of olanzapine are metabolic: acute pancreatitis is one of the most serious adverse effects; fortunately, it does not occur very often. Koller et al1 found 51 cases,and at least 13 cases have been described more precisely. We present a case study of a young female patient with a very fast and high increase of amylase and lipase, who remained asymptomatic, immediately after olanzapine treatment.
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