HPLC Coupling with ESI, MALDI and SALD ICP MS - The Detection Platform for Metalloprotein Characterization

• Title in English: HPLC Coupling with MALDI and SALD ICP MS - The Detection Platform for Metalloprotein Characterization
• Authors: JÄGEROVÁ Kateřina; BENEŠOVÁ Iva; DLABKOVÁ Kristýna; KANICKÝ Viktor; PREISLER Jan
• Year of publication: 2016
• Type: Conference abstract
• MU Faculty or unit: Faculty of Science
• Description: We demonstrate the use of a detection platform that complements conventional LC-ESI MS with two detection techniques: matrix-assisted laser desorption/ionization (MALDI) and substrate-assisted laser desorption inductively coupled plasma (SALD ICP) mass spectrometry (MS) analyses. As a model system, metallothionein 1, a low molecular protein enabling binding wide range of heavy metals (Zn,Cu,Cd,Hg) was chosen.

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