Imunoterapie v prevenci a léčbě karcinomu prsu

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Title in English Immunotherapy for the Prevention and Treatment of Breast Cancer
Authors

SVOBODA Marek NAVRÁTIL Jiří SLABÝ Ondřej

Year of publication 2015
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Central European Institute of Technology

Citation
Field Oncology and hematology
Keywords immunotherapy; breast cancer; prevention; vaccine; immune checkpoints
Description The immune system is believed to play a dual role in carcinogenesis. On one hand, it could prompt tumorigenesis and cancer progression, on the other hand, it has the capacity to eradicate tumor cells. There has been an evidence of natural immunogenicity in breast cancer and we have also witnessed several attempts to stimulate non-specific antitumor immune response (Coleys toxin, BCG vaccine etc.). New technologies and further knowledge of molecular basis of immune system and its function encouraged the development of effective immunotherapy capable of inducing a solid antitumor activity.

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