Metastázy jater a možnosti intervenční radiologie
| Title in English | Liver metastases, the role of interventional radiology |
|---|---|
| Authors | |
| Year of publication | 2015 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Other medical specializations |
| Keywords | Chemoembolization; Colorectal cancer; DEBIRI; Drug-eluting beads; Liver metastases; Liver-directed therapy; Microwaves; RFA |
| Description | Unresectable colorectal liver metastases have a 1- and 2-year survival of 55 % and 33 % with current systemic therapies. Currently image- -guided liver-directed therapy like trans-arterial chemoembolization (TACE), hepatic arterial infusion (HAI) and termoablation (RFA) has a growing role in the therapy of patients with liver metastases. Endovascular and percutaneous hepatic-directed therapy offers the dual benefit of true local neoplastic control and reduction of sideeffects. The development of new embolizing agents, such as DC beads (DEB) loaded with doxorubicin and irinotecan, permits better standardization and definition of protocols, making the procedures less linked to criteria of different hospitals and personal experiences of interventional radiologists. |