Motor cortex plasticity and excitability in Parkinson's disease

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Authors

BAREŠ Martin KAŇOVSKÝ Petr REKTOR Ivan

Year of publication 2014
Type Article in Periodical
Magazine / Source Clinical Neurophysiology
MU Faculty or unit

Faculty of Medicine

Citation
Doi http://dx.doi.org/10.1016/j.clinph.2014.01.032
Field Neurology, neurosurgery, neurosciences
Keywords INTRACORTICAL INHIBITION; PAIRED TMS; MODULATION
Attached files
Description We read with great interest the study by Kacar et al., concerning exposure to dopaminergic medication and motor cortex plasticity and excitability in Parkinson's disease (PD).The authors used a paired associative protocol (PAS), short-interval intracortical inhibition (SICI), and intracortical facilitation (1CF) to measure the sensory-motor plasticity. We would like to discuss the observation that there was no significant interaction between facilitatory sensory-motor plasticity and the features of motor cortex excitability in PD. This observation indicates that long-term treatment does not seem to change the underlying physiology of the disease.
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