Microsomes and drugs on-line incubation monitored by capillary electrophoresis couplet to mass spectrometry

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Authors

LANGMAJEROVÁ Monika ŘEMÍNEK Roman GLATZ Zdeněk

Year of publication 2014
Type Conference abstract
Citation
Description Capillary electrophoresis coupled with mass spectrometry was utilized for monitoring of enzymatic reaction, which was taken inside the capillary. Mixing of reaction components was based on general principle of diffusion. Method was used for kinetic constants measurement for system consisted of microsomes and model substrate diclofenac.
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